Which region of the adrenal gland is responsible for secreting androgens?

The zona reticularis is the innermost layer of the adrenal cortex, and it plays a critical role in the production of androgens, which are male sex hormones. These hormones include dehydroepiandrosterone (DHEA) and testosterone. The secretion of androgens is important for various physiological functions, including the development of secondary sexual characteristics and contributing to libido.

In contrast, the zona glomerulosa, which is the outermost layer of the adrenal cortex, primarily produces aldosterone, a hormone involved in regulating blood pressure and electrolyte balance. The zona fasciculata, the middle layer, is primarily involved in producing glucocorticoids, such as cortisol, which help in stress response and metabolism. Finally, the adrenal medulla is responsible for secreting catecholamines like adrenaline and norepinephrine, which are critical for the body's fight-or-flight response.

Understanding the functions of these different regions of the adrenal gland illustrates why the zona reticularis is specifically noted for androgen production, distinguishing it clearly from the roles of the other layers and the medulla.