What is the term used for the testosterone/SHBG ratio?

The term used for the testosterone/SHBG (sex hormone-binding globulin) ratio is the Free Androgen Index. This ratio is important because it provides a better estimation of the biologically active testosterone level in the body. Testosterone exists in the blood in various forms, mostly bound to proteins like SHBG. The Free Androgen Index helps to assess the amount of free, or unbound, testosterone, which is the active form that can exert effects on target tissues.

Calculating the Free Androgen Index is particularly relevant in the context of conditions associated with androgen excess, such as polycystic ovary syndrome (PCOS) or when evaluating the hormonal status of women during the menopausal transition. This index can also aid in diagnosing and managing various disorders related to hormone imbalances.

In contrast, other terms presented do not appropriately describe the testosterone/SHBG ratio. The Androgen Excess Index is a composite measure that looks at total testosterone and other factors but does not specifically refer to the testosterone/SHBG ratio. The Androstenedione Ratio specifically pertains to the hormone androstenedione, and the Estrogen Conversion Index does not relate to androgens or testosterone levels at all. These distinctions are crucial in understanding hormonal assessments