What is the definition of primary ovarian insufficiency?

Primary ovarian insufficiency, also known as premature ovarian failure, is characterized by the loss of normal ovarian function before the age of 40. This condition results in reduced estrogen production and irregular or absent menstrual periods, which can lead to early symptoms typically associated with menopause, such as hot flashes and night sweats. Women with primary ovarian insufficiency may experience fertility challenges and other hormonal imbalances due to the early loss of ovarian function.

Understanding this definition is crucial, as it helps distinguish primary ovarian insufficiency from other phases of reproductive aging and menopause. This condition can have significant physical and emotional implications, necessitating appropriate medical attention and management.