What is a key characteristic of Paget's disease regarding treatment response?

In the context of Paget's disease, a key characteristic of treatment response is that the condition typically worsens with the use of steroids. Paget's disease is a chronic skin disorder that can affect the nipple and surrounding area, often associated with underlying malignancy. Corticosteroids can have side effects that may exacerbate the symptoms of Paget's disease, such as increasing inflammation or altering skin integrity, thus leading to a decline in the patient's condition.

Understanding the nature of Paget's disease and its treatment responses is crucial for proper management. For instance, while moisturizers can provide symptomatic relief, they do not resolve the underlying pathological process of the disease, making the idea of complete resolution with them inaccurate. Other treatments might focus more on addressing the underlying causes, but they are not typically associated with an overall improvement when steroids are introduced, further underscoring the significance of recognizing worsening symptoms in response to steroid use.